Academic Dermatology

Morphological Evaluation of Micronutrient Deficiency Dermatoses in Hospitalized Patients: A Cross-Sectional Study

2024-01-16T03:22:05+00:00

INTRODUCTION: While micronutrient deficiencies are associated with classic dermatologic manifestations, there may be associated cutaneous lesions which are nonspecific. Failure to recognize heterogeneous nutritional dermatoses may result in the underdiagnosis of nutritional disease.

METHODS: A descriptive, cross-sectional analysis of 531 inpatients with dermatological conditions and laboratory confirmed micronutrient deficiencies were queried from a single institution healthcare database. Demographics and hospital outcomes were extracted from hospital records. Morphologies and locations of cutaneous lesions were extracted using a formal template from consult notes.

RESULTS: The average affected patient was overweight (mean BMI of 31.3 ±10.4 kg/m2), and less than 30% had combined protein-calorie malnutrition. Psychiatric disease (n=195, 36.7%) and chronic liver disease (n=105, 19.2%) were frequent comorbid conditions. Overall, nonspecific cutaneous presentations (n=252, 47.5%) were more common than classic presentations (n=140, 26.4%) among patients with vitamin C, A, zinc, and/or B-complex deficiencies.

CONCLUSIONS: Physicians should maintain a high index of clinical suspicion for micronutrient deficiencies, even in the absence of classic disease associations to facilitate laboratory testing and early intervention.

SARS-COV-2-19 Diagnosis Through Integration of Thermal Video and Patient Data

2023-12-21T10:07:01+00:00

INTRODUCTION: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic rapidly spread across the world, creating a need for real-time screening of individuals to prevent further transmission. We aimed to develop a mobile thermographic imaging platform, intended to scan an entrance or hallway to identify people with abnormal facial temperatures and/or vital signs.

METHODS: Adult patients who were actively symptomatic with SARS-CoV-2 infection were included along with people with other febrile illnesses, such as pneumonia or viral infection, and healthy/asymptomatic individuals, for comparison. We applied an attention-based model to conduct a thermal image-based diagnosis of the disease. Thermographic images and videos of the study subjects were obtained through a hand-held thermal camera at distances of 5 and 10 feet. Subsequently, the videos were processed and analyzed in the Photogrammetric Computer Vision Laboratory to attempt to categorize individuals with abnormal facial temperatures and vital signs.

RESULTS: Out of a total of 76 participants, 35 patients were positive for SARS-CoV-2 with active infectious syndromes, 21 were diagnosed with other infectious diseases, and the remaining 20 were asymptomatic control subjects. The dataset consists of short videos recorded by the thermal camera to indicate the temperatures of the participants. 53 videos were obtained for SARS-CoV-2 patients and 22 for non-SARS-CoV-2 patients, where 15 frames are sampled from each video at an equal distance, and each frame is resized as 224 pixels.

CONCLUSIONS: This study generated preliminary methods and results aimed at the early identification of febrile illness and can be used as a baseline for future research.

Primary Cutaneous Marginal Zone Lymphoma: A Comprehensive Review

2024-07-11T13:21:31+00:00

Primary cutaneous marginal zone lymphoma (PCMZL) represents a subset of primary cutaneous B-cell lymphomas (PCBCL) and an even smaller subset of all cutaneous lymphomas. Due to PCMZL’s indolent nature, the differentiation between PCMZL and other more aggressive PCBCLs can be challenging and result in the delay of diagnosis and treatment. The diagnosis of PCMZL requires clinical evaluation combined with immunohistochemical analysis to differentiate it from other lymphoma and non-lymphoma pathologies. The condition’s wide range of treatment options, including novel therapies, have led to various outcomes for patients diagnosed with PCMZL. This comprehensive review article emphasizes the clinical presentation and the methods of diagnosis, including appropriate pathologic evaluation, differentiating factors from other non-PCMZL conditions, and current treatment options for PCMZL.

Risk of OverDocumentation of Informed Consent Needs to be Considered Among Dermatology Journals

2024-06-19T07:29:06+00:00

No abstract available.